Prenatal developmental toxicity study of an alkaloid-free Ageratum conyzoides extract powder in rats by oral administration
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منابع مشابه
Serum protein and enzyme levels in rats following administration of ethanolic leaf extract of Ageratum conyzoides (goat weed).
The The potential hepatotoxic effects following oral administration of ethanolic leaf extract of Ageratum conyzoides (goat weed) was investigated in albino Wistar rats. Twenty eight (28) adult male Wistar rats were uniformly divided into four groups of seven rats each. Group 1 served as control while groups 2, 3 and 4 were respectively gavaged with 200 mg/kg body weight, 400 mg/kg body weight a...
متن کاملHaematopoietic properties of ethanolic extract of Ageratum conyzoides (goat weed) in albino rats.
The potential haematological effects associated with the administration of ethanolic leaf extract of Ageratum conyzoides was investigated in rats. 27 rats were randomly divided into four groups. The first group had 6 rats and served as control, the remaining 3 experimental groups and had 7 rats each. These later groups were gavaged with the extract of Ageratum conyzoides in concentrations of 20...
متن کاملAcute and Sub-chronic (28-day) Oral Toxicity Studies of Hydroalcohol Leaf Extract of Ageratum conyzoides L (Asteraceae)
Purpose: Ageratum conyzoides is an annual herbaceous plant commonly used in African traditional medicine as a purgative, antipyretic, anti-ulcer and wound dressing agent. The objective of this study was to investigate the acute and sub-chronic toxicity of A. conyzoides leaves in Wistar rats. Methods: In the acute test, the limit test dose of 5000 mg/kg was administered to Wistar rats and then o...
متن کاملDevelopmental toxicity of N-methylaniline following prenatal oral administration in rats.
OBJECTIVES The objective of the study was to assess prenatal toxicity of N-methylaniline (NMA) administered by gavage to pregnant female rats. MATERIAL AND METHODS Pregnant female rats were administered N-methylaniline in corn oil by gavage at daily doses of 0.8 mg/kg of body weight (b.w.), 4 mg/kg b.w., 20 mg/kg b.w. and 100 mg/kg b.w. from implantation (the 5th day post mating) to the day p...
متن کاملHypoglycaemic and antihyperglycaemic activity of Ageratum conyzoides L. in rats.
The hypoglycaemic and antihyperglycaemic properties of the aqueous extracts of the leaves of Ageratum conyzoides L. were evaluated in normoglycemic and in streptozotocin-induced diabetic rats, in order to validate its use in folk medicine. Tested animals were given the aqueous extracts of the plant at the doses of 100, 200 and 300mg/kg. These doses were tested also on glucose loaded normal male...
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ژورنال
عنوان ژورنال: Regulatory Toxicology and Pharmacology
سال: 2020
ISSN: 0273-2300
DOI: 10.1016/j.yrtph.2020.104748